MODIFIERAD VAEVNADS-PLASMIN-AKTIVATOR

Novel modified tissue plasminogen activators (t-PA) are described. The novel t-PA's are single-chained molecules being cleaved at one or more positions in the peptide sequence extending from Cys(409) to Cys(44l) and capable of being activated in the presence of plasmin. The novel products are f...

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Bibliographische Detailangaben
Hauptverfasser:	WALLEN, PER BRUNO, NORRMAN, BO ANDERS, NEXO, BJORN ANDERSEN
Format:	Patent
Sprache:	fin
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	Novel modified tissue plasminogen activators (t-PA) are described. The novel t-PA's are single-chained molecules being cleaved at one or more positions in the peptide sequence extending from Cys(409) to Cys(44l) and capable of being activated in the presence of plasmin. The novel products are formed by cleavage of tissues plasminogen activators and are useful in treatment of vascular disorders.