FOERFARANDE FOER FRAMSTAELLNING AV ANTIBAKTERIELLT AKTIVA 6-HALOGEN-7-AMINO-4-OXO-4H-/1,3/TIAZETO/3,2-A/KINOLIN-3-KARBOXYLSYRADERIVAT

FOERFARANDE FOER FRAMSTAELLNING AV ANTIBAKTERIELLT AKTIVA 6-HALOGEN-7-AMINO-4-OXO-4H-/1,3/TIAZETO/3,2-A/KINOLIN-3-KARBOXYLSYRADERIVAT

Quinolinecarboxylic acid derivatives represented by the following general formula (I) and physiologically-acceptable salts thereof. wherein R is hydrogen, alkyl, or substituted or unsubstituted phenyl; R is hydrogen, alkyl, aikoxy, hydroxy, halogen, nitro or substituted or unsubstituted amino; R is...

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Hauptverfasser: SHIRAHASE,ICHIRO, KAZUNO,KENJI, SEGAWA,JUN, OZAKI,MASAKUNI, TOMII,YOSHIFUMI, KISE,MASAHIRO, KITANO,MASAHIKO
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Sprache:fin ; swe
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Quinolinecarboxylic acid derivatives represented by the following general formula (I) and physiologically-acceptable salts thereof. wherein R is hydrogen, alkyl, or substituted or unsubstituted phenyl; R is hydrogen, alkyl, aikoxy, hydroxy, halogen, nitro or substituted or unsubstituted amino; R is hydrogen or optionally-substituted alkyl; R and R are same or different and are alkyl or hydroxyalkyl or R and R may be combined and may form a cyclic amino together with the adjacent nitrogen atom and said cyclic amino may also be substituted and may further contain nitrogen, oxygen or sulfur as hetero-atoms therein; and X is halogen. have been found to be very effective antibacterial therapeutic agents for systemic and local infectious diseases caused by P. aeruginosa and Grampositive and negative bacteria.