NYA 1-BENZYL-3,4-DIHYDRO-ISOKINOLINDERIVAT

The invention relates to the new 6,7-diethoxy-1-(4-ethoxy-3-hydroxy-benzyl)-3,4-dihydro-isoquinoline of the Formula I and physiologically acceptable salts thereof. The compound of the Formula I and salts thereof can be prepared by hydrolysing a compound of the general Formula VI (wherein R is a group removable by hydrogenolysis) preferably a benzyl group and R is an alkyl group having 1-6 carbon atoms), reacting the compound of the general Formula V thus obtained (wherein R is as stated above) with an amine of the general Formula IV or a salt thereof in the presence of a catalyst, subjecting the amide of the general Formula III thus obtained (wherein R is as stated above) to ring-closure and subjecting the compound of the General Formula II (wherein R is as stated above) or a salt thereof thus obtained to hydrogenolysis and if desired converting the compound of the Formula I thus obtained into a physiologically acceptable salt thereof or setting free the same from its salt.