HETEROCYKLISKA DERIVAT AV AMIDOXIMER, DERAS FRAMSTAELLNING OCH TILLAEMPNING VID BEHANDLING AV SJUKDOMAR

Heterocyclic amidoxime derivatives of the general formula: wherein R' represents hydrogen or the methyl radical, and R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-i...

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1. Verfasser: OBITZ, DANIEL
Format: Patent
Sprache:fin
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Zusammenfassung:Heterocyclic amidoxime derivatives of the general formula: wherein R' represents hydrogen or the methyl radical, and R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-isoindol-2-yl, 2-oxo-3,4-dihydro-2_H-quinolin-1-yl, 5-chloro-3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl, 5-chloro-2-oxo-3-phenyl-2,3-dihydro-1_H-benzimidazol-1-yl, 4-chloro-1-oxo-1_H-isoquinolin-2-yl or 3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl radical, and-when R' represents the methyl radical-racemates and enantiomers of such compounds, are new compounds useful in therapy, and especially for the treatment of complaints of the central nervous system and for the treatment of depression.