FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA 1-(HYDROXIMETYL)-1,6,7,11B-TETRAHYDRO-2H,4H- /1,3/OXAZINO- ELLER TIAZINO/4,3-A/ISOKINOLINDERIVAT

The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), (I) wherein R1 and R2 are alkoxy having from 1 to 6 carbon atoms, X is oxygen or sulfur, Y is =O, =S or an =NR3 group, wherein R3 is hydrogen, alkyl ha...

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Hauptverfasser: EZER, ELEMER, SOHAJDA, ATTILA, FUELOEP, FERENC, KOBOR, JENOE, SPORNY, LASZLO, HAJOS, GYOERGY, BERNATH, GABOR, KALMAN, ALAJOS, PALOSI, EVA, DENES, LASZLO
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Sprache:fin
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Zusammenfassung:The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), (I) wherein R1 and R2 are alkoxy having from 1 to 6 carbon atoms, X is oxygen or sulfur, Y is =O, =S or an =NR3 group, wherein R3 is hydrogen, alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms or optionally substituted phenyl, and acid addition and quaternary salts thereof.