FOERFARANDE FOER FRAMSTAELLNING AV 5(6)-TIOBENSIMIDAZOLDERIVAT

A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts...

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Bibliographische Detailangaben
Hauptverfasser:	GOENCZI, CSABA, PALOSI, ANDRE, SZVOBODA, GYOERGYNE, KELEMEN, ANDRAS, KISS, PAL, KOERMOECZI, GYOERGY, SZOMOR, TIBORNE, CSER, GABORNE, HEJA, GERGELY, KORBONITS, DEZSO
Format:	Patent
Sprache:	fin
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRAPPING
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Beschreibung
Zusammenfassung:	A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: to reduction to cleave the disulfide linkage and where R4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed.