FOERFARANDE FOER SELEKTIV FRAMSTAELLNING AV 3-OXO-20-METYLPREGNA-4,20(21)-DIEN-21-YLACETAT

The present invention relates to the selective conversion of 20-methylpregna-3,5,20(21)-triene-3,21-diol-diacetate to 3-oxo-20-methylpregna-4,20(21)- diene-21-yl-acetate by the use of a halogenated solvent and a halogenated acid. This process provides improved recovery of 3-oxo-20-methylpregna-4,20(...

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1. Verfasser: KRBECHEK LEROY
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Sprache:fin
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Zusammenfassung:The present invention relates to the selective conversion of 20-methylpregna-3,5,20(21)-triene-3,21-diol-diacetate to 3-oxo-20-methylpregna-4,20(21)- diene-21-yl-acetate by the use of a halogenated solvent and a halogenated acid. This process provides improved recovery of 3-oxo-20-methylpregna-4,20(21)- diene-21-yl acetate which is a useful intermediate in the preparation of progesterone.