FOERFARANDE FOER FRAMSTAELLNING AV NYA 1- OCH D1-6-(M-(ISOTIAZOL-5-KARBOXIAMIDO)FENYL)-2,3,5,6-TETRAHYDROIMIDAZO(2,1-B)TIAZOLDERIVAT VILKA ANVAENDS SOM MASKMEDEL

FOERFARANDE FOER FRAMSTAELLNING AV NYA 1- OCH D1-6-(M-(ISOTIAZOL-5-KARBOXIAMIDO)FENYL)-2,3,5,6-TETRAHYDROIMIDAZO(2,1-B)TIAZOLDERIVAT VILKA ANVAENDS SOM MASKMEDEL

A procedure for the preparation of forms l and dl (racemic) of a compound of formula: * (See formula I) * where R is H or CH3, or a non-toxic acid addition salt thereof, the procedure of which is to make react the dl-6- (m-aminophenyl) -2,3,5,6-tetrahydroimidazo [2,1-b] thiazole with an acid of the...

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Hauptverfasser: LEEMING MICHAEL RAYMOND GRAVES, STUBBS JOHN KENDRICK
Format: Patent
Sprache:fin
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A procedure for the preparation of forms l and dl (racemic) of a compound of formula: * (See formula I) * where R is H or CH3, or a non-toxic acid addition salt thereof, the procedure of which is to make react the dl-6- (m-aminophenyl) -2,3,5,6-tetrahydroimidazo [2,1-b] thiazole with an acid of the formula: * (See formula III) * Where R is the one defined above or with its functional equivalent as acylating agent, optionally followed by i) when form dl is used to obtain form l or ii) conversion of the product into a non-toxic acid addition salt with a suitable acid. (Machine-translation by Google Translate, not legally binding)