Menetelmä uuden liukoisen antibioottisen aktiviteetin ja alhaisen myrk yllisyyden omaavan 4-guanyyliatso-4-desoksi-rifamysiini SV:n 25-desase tyylijohdannaisen valmistamiseksi

Menetelmä uuden liukoisen antibioottisen aktiviteetin ja alhaisen myrk yllisyyden omaavan 4-guanyyliatso-4-desoksi-rifamysiini SV:n 25-desase tyylijohdannaisen valmistamiseksi

The invention is concerned with a new class of rifamycins, namely, the 25-desacetylrifamycins, and with a process for their preparation. The new compounds display antibacterial activity quite similar to that shown by the parent 25-acetylrifamycins, and are characterized by a higher solubility and a...

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Bibliographische Detailangaben
Hauptverfasser: MAGGI,NICOLA, SENSI,PIERO
Format: Patent
Sprache:fin ; swe
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:The invention is concerned with a new class of rifamycins, namely, the 25-desacetylrifamycins, and with a process for their preparation. The new compounds display antibacterial activity quite similar to that shown by the parent 25-acetylrifamycins, and are characterized by a higher solubility and a lower toxicity than the parent substances.