N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to derivatives of formula (I)wherein (R1)n, R2, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or...

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Bibliographische Detailangaben
Hauptverfasser:	LYOTHIER, Isabelle, WYDER PETERS, Lorenza, RICHARD-BILDSTEIN, Sylvia, POTHIER, Julien, POZZI, Davide, SIFFERLEN, Thierry, FRETZ, Heinz, CORMINBOEUF, Olivier
Format:	Patent
Sprache:	eng ; fin
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to derivatives of formula (I)wherein (R1)n, R2, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.