8-CYANO-5-PIPERIDINO-QUINOLINES AS TLR7/8 ANTAGONISTS AND THEIR USES FOR TREATING IMMUNE DISORDERS

The invention relates to the cis racemic, cis isomer 1 and cis isomer 2 forms of following compound, useful as TLR7/8 antagonists for treating e.g. systemic lupus erythematosus, and to pharmaceutically acceptable compositions thereof.

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Bibliographische Detailangaben
Hauptverfasser:	Brugger, Nadia, Sherer, Brian
Format:	Patent
Sprache:	eng ; fin
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to the cis racemic, cis isomer 1 and cis isomer 2 forms of following compound, useful as TLR7/8 antagonists for treating e.g. systemic lupus erythematosus, and to pharmaceutically acceptable compositions thereof.