TETRAHYDROPYRANYL AMINO-PYRROLOPYRIMIDINONE FOR USE IN TREATING BTK-MEDIATED DISORDERS

The application relates to a compound of Formula (I):or a pharmaceutically acceptable salt, tautomer, prodrug, solvate or polymorph thereof, for use in a method of treating a BTK disorder or of modulating BTK, wherein the BTK is mutant BTK (e.g., BTK C481S mutant)

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Bibliographische Detailangaben
Hauptverfasser:	OTA, Yusuke, EATHIRAJ, Sudharshan, LAPIERRE, Jean-Marc, SCHWARTZ, Brian, NAMDEV, Nivedita, INAGAKI, Hiroaki, NAKAYAMA, Kiyoshi, MOMOSE, Takayuki, TSUNEMI, Tomoyuki
Format:	Patent
Sprache:	eng ; fin
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The application relates to a compound of Formula (I):or a pharmaceutically acceptable salt, tautomer, prodrug, solvate or polymorph thereof, for use in a method of treating a BTK disorder or of modulating BTK, wherein the BTK is mutant BTK (e.g., BTK C481S mutant)