ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES

ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES

Drug conjugates having formula [D-(X)6-(AA)w-(T)g-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, (I) wherein D is covalently attached via a hydroxy or amine group to (X)b if any, or (AA)w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LATORRE LOZANO, Alfonso, CUEVAS MARCHANTE, Maria del Carmen, FRANCESCH SOLLOSO, Andres, MARTINEZ BARRASA, Valentin
Format: Patent
Sprache:eng ; fin ; swe
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Drug conjugates having formula [D-(X)6-(AA)w-(T)g-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, (I) wherein D is covalently attached via a hydroxy or amine group to (X)b if any, or (AA)w if any, or to (T)g if any, or (L); that are useful in the treatment of cancer.