IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses compounds according to Formula I:Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein.The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the sam...

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Hauptverfasser: COTI, Ghjuvanni, CLAES, Pieter, MARTINA, Sébastien, MAMMOLITI, Oscar, AMANTINI, David, LÓPEZ RAMOS, Miriam, ANNOOT, Denis, GALIEN, René, VAN DER PLAS, Steven, BRYS, Reginald
Format: Patent
Sprache:eng ; fin
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Zusammenfassung:The present invention discloses compounds according to Formula I:Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein.The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, auto inflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFNα, IL12 and/or IL23 by administering the compound of the invention.