COMBINATION COMPRISING A STABLE CRYSTAL OF A 4-OXOQUINOLINE COMPOUND

The present invention provides a crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, which shows a particular powder X-ray diffraction pattern of a characteristic diffraction peaks at diffraction angles 2θ(°) as measur...

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Bibliographische Detailangaben
Hauptverfasser: MATSUDA, Koji, KONDO, Kentaro, ANDO, Koji, SATOH, Motohide, MOTOMURA, Takahisa, UEHARA, Hideto, MIYAKE, Shuji, MATSUDA, Takashi
Format: Patent
Sprache:eng ; fin
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Zusammenfassung:The present invention provides a crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, which shows a particular powder X-ray diffraction pattern of a characteristic diffraction peaks at diffraction angles 2θ(°) as measured by powder X-ray diffractometry. The crystal of the present invention is superior in physical and chemical stability.