POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT

The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, .beta.-blockers and mix...

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Bibliographische Detailangaben
Hauptverfasser: SULISTIO, Adrian, NG, Sarah, TAIT, Russell, DONOHUE, Andrew, BLENCOWE, Anton, BIRKETT, Stephen
Format: Patent
Sprache:eng ; fin
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Zusammenfassung:The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, .beta.-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.