Derivados de rapamicina que contienen 1,1-dióxido de isotiazolidina y 1,4-butanosultona y usos de los mismos

Derivados de rapamicina que contienen 1,1-dióxido de isotiazolidina y 1,4-butanosultona y usos de los mismos

Described herein are compounds of Formula (I) that are inhibitors of mTORC1, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

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Bibliographische Detailangaben
Hauptverfasser: GLASS, David J, CONNOLLY, Michael, PATTERSON, Andrew W, BONAZZI, Simone, SHAVLAKADZE, Tea
Format: Patent
Sprache:spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Described herein are compounds of Formula (I) that are inhibitors of mTORC1, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.