Procedimientos terapéuticos y de diagnóstico para enfermedades autoinmunes y/o inflamación

The present invention features methods of treating a subject having an autoimmune disease and/or inflammation including determining the genotype, and/or the glycophenotype of the subject and administering to the subject an Fc-activity modulating agent or an anti-TNFα agent based on the genotype and/...

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Bibliographische Detailangaben
Hauptverfasser: HALVEY, Patrick, CAPILA, Ishan, MCCONNELL, Kevin, MANNING, Anthony, WASHBURN, Nathaniel, FARUTIN, Victor, LING, Leona
Format: Patent
Sprache:spa
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Beschreibung
Zusammenfassung:The present invention features methods of treating a subject having an autoimmune disease and/or inflammation including determining the genotype, and/or the glycophenotype of the subject and administering to the subject an Fc-activity modulating agent or an anti-TNFα agent based on the genotype and/or the glycophenotype of the subject. The invention also features methods of predicting the responsiveness of a patient to an anti-TNFα treatment by identifying a patient having inflammation or an autoimmune disease, determining the genotype, or glycophenotype of the subject, and selecting the patient for treatment with an Fc-activity modulating agent or an anti-TNFα agent based on the genotype and/or the glycophenotype of the subject.