Composición farmacéutica que comprende disulfuro de glutatión y disulfuro de glutatión S-óxido

Una composición farmacéutica que comprende disulfuro de glutatión o sal orgánica o inorgánica farmacéuticamente aceptable del mismo y disulfuro de glutatión S-óxido de la siguiente estructura: o sal orgánica o inorgánica farmacéuticamente aceptable de la misma, para su uso como medicamento. or pharmaceutically acceptable organic or inorganic salt thereof for eliminating dose-related toxicity and enhancing the therapeutic activity of a pharmacologically active compound in the treatment of infectious and non-infectious diseases is provided. Typically, the composition comprises glutathione disulfide S-oxide in an amount of 0.01-10% by weight of the total composition, and additionally a metal (Me) in the form of coordination compound(s) containing Me-S-glutathione bond, said metal is selected from the platinum group, typically it is platinum. The amount of d-metal coordination compound administered to a patient can be 10−3 to 10−15 mol/kg of body weight. The composition can be used in combination with pharmacologically active compound, which is an anticoagulant, factor Xa inhibitor, antimicrobial or antiviral agents to increase their therapeutic activity and eliminate dose-related toxicity.