Compuesto espiro tricíclico
Un compuesto seleccionado de acido 4-[4-ciano-2-({[(2'R,4S)-6-(isopropilcarbamoil)-2,3-dihidroespiro[cromen-4,1'- ciclopropan]-2'-il]carbonil}amino)fenil]butanoico, una sal del mismo y un solvato del mismo. Provided herein is a medicinal agent for the prevention and/or treatment of di...
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| creator | FUCHIBE, Kazuhiro KOTANI, Tohru ASADA, Masaki TANI, Kousuke OIKAWA, Ryo HIROBE, Masaya TAKANO, Hirotsugu HIGUCHI, Satonori |
| description | Un compuesto seleccionado de acido 4-[4-ciano-2-({[(2'R,4S)-6-(isopropilcarbamoil)-2,3-dihidroespiro[cromen-4,1'- ciclopropan]-2'-il]carbonil}amino)fenil]butanoico, una sal del mismo y un solvato del mismo.
Provided herein is a medicinal agent for the prevention and/or treatment of diseases caused by SP4 receptor activation. A compound having antagonistic activity against the EP4 receptor is contained as an active ingredient in the medicinal agent. The compound represented by the following general formula (I), a salt, an N-oxide, or a solvate thereof, or a prodrug of these is useful as a medicinal component having antagonistic activity against the EP4 receptor for the prevention and/or treatment of diseases caused by EP4 receptor activation.In the formula, all symbols are as defined in the specification. |
| format | Patent |
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Provided herein is a medicinal agent for the prevention and/or treatment of diseases caused by SP4 receptor activation. A compound having antagonistic activity against the EP4 receptor is contained as an active ingredient in the medicinal agent. The compound represented by the following general formula (I), a salt, an N-oxide, or a solvate thereof, or a prodrug of these is useful as a medicinal component having antagonistic activity against the EP4 receptor for the prevention and/or treatment of diseases caused by EP4 receptor activation.In the formula, all symbols are as defined in the specification.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210705&DB=EPODOC&CC=ES&NR=2839203T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210705&DB=EPODOC&CC=ES&NR=2839203T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FUCHIBE, Kazuhiro</creatorcontrib><creatorcontrib>KOTANI, Tohru</creatorcontrib><creatorcontrib>ASADA, Masaki</creatorcontrib><creatorcontrib>TANI, Kousuke</creatorcontrib><creatorcontrib>OIKAWA, Ryo</creatorcontrib><creatorcontrib>HIROBE, Masaya</creatorcontrib><creatorcontrib>TAKANO, Hirotsugu</creatorcontrib><creatorcontrib>HIGUCHI, Satonori</creatorcontrib><title>Compuesto espiro tricíclico</title><description>Un compuesto seleccionado de acido 4-[4-ciano-2-({[(2'R,4S)-6-(isopropilcarbamoil)-2,3-dihidroespiro[cromen-4,1'- ciclopropan]-2'-il]carbonil}amino)fenil]butanoico, una sal del mismo y un solvato del mismo.
Provided herein is a medicinal agent for the prevention and/or treatment of diseases caused by SP4 receptor activation. A compound having antagonistic activity against the EP4 receptor is contained as an active ingredient in the medicinal agent. The compound represented by the following general formula (I), a salt, an N-oxide, or a solvate thereof, or a prodrug of these is useful as a medicinal component having antagonistic activity against the EP4 receptor for the prevention and/or treatment of diseases caused by EP4 receptor activation.In the formula, all symbols are as defined in the specification.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBxzs8tKE0tLslXSC0uyCzKVygpykw-vDY5JzM5n4eBNS0xpziVF0pzMyi6uYY4e-imFuTHA5UnJqfmpZbEuwYbWRhbGhkYh4QYGxOjBgANRSU4</recordid><startdate>20210705</startdate><enddate>20210705</enddate><creator>FUCHIBE, Kazuhiro</creator><creator>KOTANI, Tohru</creator><creator>ASADA, Masaki</creator><creator>TANI, Kousuke</creator><creator>OIKAWA, Ryo</creator><creator>HIROBE, Masaya</creator><creator>TAKANO, Hirotsugu</creator><creator>HIGUCHI, Satonori</creator><scope>EVB</scope></search><sort><creationdate>20210705</creationdate><title>Compuesto espiro tricíclico</title><author>FUCHIBE, Kazuhiro ; KOTANI, Tohru ; ASADA, Masaki ; TANI, Kousuke ; OIKAWA, Ryo ; HIROBE, Masaya ; TAKANO, Hirotsugu ; HIGUCHI, Satonori</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2839203TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FUCHIBE, Kazuhiro</creatorcontrib><creatorcontrib>KOTANI, Tohru</creatorcontrib><creatorcontrib>ASADA, Masaki</creatorcontrib><creatorcontrib>TANI, Kousuke</creatorcontrib><creatorcontrib>OIKAWA, Ryo</creatorcontrib><creatorcontrib>HIROBE, Masaya</creatorcontrib><creatorcontrib>TAKANO, Hirotsugu</creatorcontrib><creatorcontrib>HIGUCHI, Satonori</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FUCHIBE, Kazuhiro</au><au>KOTANI, Tohru</au><au>ASADA, Masaki</au><au>TANI, Kousuke</au><au>OIKAWA, Ryo</au><au>HIROBE, Masaya</au><au>TAKANO, Hirotsugu</au><au>HIGUCHI, Satonori</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Compuesto espiro tricíclico</title><date>2021-07-05</date><risdate>2021</risdate><abstract>Un compuesto seleccionado de acido 4-[4-ciano-2-({[(2'R,4S)-6-(isopropilcarbamoil)-2,3-dihidroespiro[cromen-4,1'- ciclopropan]-2'-il]carbonil}amino)fenil]butanoico, una sal del mismo y un solvato del mismo.
Provided herein is a medicinal agent for the prevention and/or treatment of diseases caused by SP4 receptor activation. A compound having antagonistic activity against the EP4 receptor is contained as an active ingredient in the medicinal agent. The compound represented by the following general formula (I), a salt, an N-oxide, or a solvate thereof, or a prodrug of these is useful as a medicinal component having antagonistic activity against the EP4 receptor for the prevention and/or treatment of diseases caused by EP4 receptor activation.In the formula, all symbols are as defined in the specification.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Compuesto espiro tricíclico |
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