Compuesto espiro tricíclico

Un compuesto seleccionado de acido 4-[4-ciano-2-({[(2'R,4S)-6-(isopropilcarbamoil)-2,3-dihidroespiro[cromen-4,1'- ciclopropan]-2'-il]carbonil}amino)fenil]butanoico, una sal del mismo y un solvato del mismo. Provided herein is a medicinal agent for the prevention and/or treatment of di...

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Bibliographische Detailangaben
Hauptverfasser:	FUCHIBE, Kazuhiro, KOTANI, Tohru, ASADA, Masaki, TANI, Kousuke, OIKAWA, Ryo, HIROBE, Masaya, TAKANO, Hirotsugu, HIGUCHI, Satonori
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Un compuesto seleccionado de acido 4-[4-ciano-2-({[(2'R,4S)-6-(isopropilcarbamoil)-2,3-dihidroespiro[cromen-4,1'- ciclopropan]-2'-il]carbonil}amino)fenil]butanoico, una sal del mismo y un solvato del mismo. Provided herein is a medicinal agent for the prevention and/or treatment of diseases caused by SP4 receptor activation. A compound having antagonistic activity against the EP4 receptor is contained as an active ingredient in the medicinal agent. The compound represented by the following general formula (I), a salt, an N-oxide, or a solvate thereof, or a prodrug of these is useful as a medicinal component having antagonistic activity against the EP4 receptor for the prevention and/or treatment of diseases caused by EP4 receptor activation.In the formula, all symbols are as defined in the specification.