Indolocarbazoles glicosilados, procedimiento de obtención y usos de los mismos

Un compuesto seleccionado de entre el grupo: **(Ver fórmula)** o una sal o solvato farmacéuticamente aceptable del mismo. Glycosylated indolocarbazoles of formula (II), method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermen...

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Hauptverfasser: FERNANDEZ BRANA, Alfredo, MORIS VARAS, Francisco, PEREZ SALAS, Aaroa, SALAS FERNANDEZ, Jose Antonio, MENDEZ FERNANDEZ, Carmen, SANCHEZ REILLO, César
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creator FERNANDEZ BRANA, Alfredo
MORIS VARAS, Francisco
PEREZ SALAS, Aaroa
SALAS FERNANDEZ, Jose Antonio
MENDEZ FERNANDEZ, Carmen
SANCHEZ REILLO, César
description Un compuesto seleccionado de entre el grupo: **(Ver fórmula)** o una sal o solvato farmacéuticamente aceptable del mismo. Glycosylated indolocarbazoles of formula (II), method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.
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Glycosylated indolocarbazoles of formula (II), method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title Indolocarbazoles glicosilados, procedimiento de obtención y usos de los mismos
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