Indolocarbazoles glicosilados, procedimiento de obtención y usos de los mismos

Un compuesto seleccionado de entre el grupo: **(Ver fórmula)** o una sal o solvato farmacéuticamente aceptable del mismo. Glycosylated indolocarbazoles of formula (II), method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermen...

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Hauptverfasser: FERNANDEZ BRANA, Alfredo, MORIS VARAS, Francisco, PEREZ SALAS, Aaroa, SALAS FERNANDEZ, Jose Antonio, MENDEZ FERNANDEZ, Carmen, SANCHEZ REILLO, César
Format: Patent
Sprache:spa
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Zusammenfassung:Un compuesto seleccionado de entre el grupo: **(Ver fórmula)** o una sal o solvato farmacéuticamente aceptable del mismo. Glycosylated indolocarbazoles of formula (II), method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.