PROTEINA RECOMBINANTE DE NANNOCHLOROPSIS GADITANA

The present invention relates to the use of a recombinant protein as a cancer growth inhibitor, specifically to the use of the recombinant prohibitin UCA01, which is a protein that immerses the cell in a period of miotic inactivity in the case of cancer cells. In this way, the protein prevents cance...

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Bibliographische Detailangaben
Hauptverfasser:	SORIANO ROMANI, Laura, FERNANDEZ ACERO, Francisco Javier, ESCOBAR NINO, Almudena, ANDRES VALLEJO, Roberto, GUARNIZO GARCIA, Palmira, FAJARDO QUINONES, Carlos, CAPILLA LOPEZ, Victoria, TOMAS COBOS, Lidia, CARRASCO REINADO, Rafael
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the use of a recombinant protein as a cancer growth inhibitor, specifically to the use of the recombinant prohibitin UCA01, which is a protein that immerses the cell in a period of miotic inactivity in the case of cancer cells. In this way, the protein prevents cancer growth and the onset of same. UCA01 prevents the onset of cancer, owing to three factors: its antioxidant capacity; increased p53 protein activity; and protection of the mitochondria against degradation. Specifically, the invention shows, for the first time, the biological activity of the recombinant protein UCA01, extracted from microalgae (Nannochloropsis gaditana). Before this invention, wild UCA01 protein was initially classified as a hypothetical protein in the National Center for Biotechnology Information (NCBI) (accession: XM_005854224.1).