Procedure to identify properties of a grape extract (Machine-translation by Google Translate, not legally binding)

The invention involves a series of processes that establish the solubility, non-cytotoxic and cytotoxic concentrations of grape extract, subsequently establishing its antioxidant and antidegenerative capacity and its efficacy using human retinal pigment epithelial cell cultures and various assay strategies that combine different oxidative treatments. Additionally, a composition for treating or ameliorating an ophthalmological disorder is described, which comprises a grape extract. (Machine-translation by Google Translate, not legally binding) La invención implica una serie de procesos que establecen la solubilidad, las concentraciones no-citotóxicas y citotóxicas del extracto de uva, posteriormente estableciendo su capacidad antioxidante y antidegenerativa y su eficacia utilizando cultivos de células epiteliales pigmentarias retinales humanas y diversas estrategias de ensayo que combinan diferentes tratamientos oxidativos. Adicionalmente, se describe una composición para tratar o mejorar un trastorno oftalmológico, que comprende un extracto de uva.