Composición farmacéutica de microesferas de liberación sostenida de goserelina

A composition of goserelin sustained release microsphere is provided. The microspheres comprise goserelin, at least one poly (lactide-co-glycolide) and poloxamer or PEG. The sustained release microspheres have comparatively high bioavailability, which promotes the drug taking its full effect and hav...

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Bibliographische Detailangaben
Hauptverfasser:	LI, Youxin, SUN, Wei, LENG, Guangyi, SUN, Kaoxiang, LIU, Wanhui, ZHANG, Xuemei, WANG, Tao
Format:	Patent
Sprache:	spa
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	A composition of goserelin sustained release microsphere is provided. The microspheres comprise goserelin, at least one poly (lactide-co-glycolide) and poloxamer or PEG. The sustained release microspheres have comparatively high bioavailability, which promotes the drug taking its full effect and have entrapment efficiency over 90%.