Método para detectar pólipos gástricos y cáncer gástrico utilizando un gen marcador de pólipos gástricos y metilación específica del cáncer gástrico

Uso de una isla CpG metilada del gen sindecan-2 (SDC2) localizada en una región establecida en la SEQ ID NO: 1 para diagnosticar cáncer gástrico o pólipo gástrico. The present invention relates to the novel use of syndecan-2 (SDC2; NM_002998) gene as a gastric polyp- and gastric cancer-specific methylation biomarker, and more particularly, to the use of the syndecan-2 gene as a biomarker that enables gastric polyp and gastric cancer to be diagnosed in an early stage by measuring the methylation level thereof. The present invention has an effect in that the methylation of the CpG island of the gastric polyp- and gastric cancer-specific marker gene can be detected to thereby provide information for diagnosing gastric cancer. The use of the methylation detection method according to the present invention or the diagnostic composition, kit or nucleic acid chip according to the present invention makes it possible to diagnose gastric cancer at an early transformation stage, thus enabling the early diagnosis of gastric cancer. In addition, the method of the present invention enables gastric cancer to be effectively diagnosed in an accurate and rapid manner compared to conventional methods.