Intermediario 2-aril ciclopropano carboxamida ópticamente activo

Intermediario 2-aril ciclopropano carboxamida ópticamente activo

El compuesto (1R, 2R)-2-(3,4-difluorofenil)-1-ciclopropanocarboxamida. This invention relates to optically active 2-(disubstituted aryl) cyclopropane carboxamide derivatives which are useful intermediates for the preparation of pharmaceutical agents, and in particular the compound [1 S -(1±, 2±, 3²...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moroshima, Tadashi, Tsukuya, Kentaro, Yamada, Masahiko, Mitsuda, Masaru, Watabe, Kazuhiko
Format: Patent
Sprache:spa
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:El compuesto (1R, 2R)-2-(3,4-difluorofenil)-1-ciclopropanocarboxamida. This invention relates to optically active 2-(disubstituted aryl) cyclopropane carboxamide derivatives which are useful intermediates for the preparation of pharmaceutical agents, and in particular the compound [1 S -(1±, 2±, 3² (1 S *,2 R *),5²)]-3-[7-[2-(3,4-difluorophenyl)-cyclopropyl]amino]-5-(propylthio)-3 H -1,2,3-triazolo[4,5- d ]pyrimidin-3-yl)-5-(2-hydroxyethoxy)-cyclopentane-1,2-diol.