In vitro method for predicting and/or forecasting the compatibility of biomaterials in a subject (Machine-translation by Google Translate, not legally binding)

In vitro method to predict and/or predict the compatibility of biomaterials in a subject. The present invention relates to a set of markers, preferably proteins, all related to the pathway of the complement activation system, which are particularly useful for predicting and/or predicting the in vitr...

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Bibliographische Detailangaben
Hauptverfasser: Suay Antón, Julio José, Gurruchaga Torrecilla, Mariló, Sanchez Pérez, Ana María, Goñi Echave, Isabel, Elortza Basterrika, Félix
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:In vitro method to predict and/or predict the compatibility of biomaterials in a subject. The present invention relates to a set of markers, preferably proteins, all related to the pathway of the complement activation system, which are particularly useful for predicting and/or predicting the in vitro compatibility of a biomaterial, such as, for example, joint prostheses, dental prostheses, valves, stens, etc., in your subject. Additionally, the present invention comprises an in vitro method for predicting and/or predicting the compatibility of said materials by determining the peptide profile described in the invention, as well as a kit and/or device for carrying out said method. (Machine-translation by Google Translate, not legally binding) Método in vitro para predecir y/o pronosticar la compatibilidad de biomateriales en un sujeto. La presente invención se refiere a un conjunto de marcadores, preferentemente proteínas, todas ellas relacionadas con la vía del sistema de activación del complemento, que son particularmente útiles para predecir y/o pronosticar la compatibilidad in vitro de un biomaterial, tal como por ejemplo, prótesis articulares, prótesis dentales, válvulas, stens, etc., en su sujeto. Adicionalmente, la presente invención comprende un método in vitro para predecir y/o pronosticar la compatibilidad de dichos materiales mediante la determinación del perfil peptídico descrito en la invención, así como un kit y/o dispositivo para llevar a cabo dicho método.