Genetically modified microbial cell with improved tolerance to alcohols (Machine-translation by Google Translate, not legally binding)

Genetically modified microbial cell with improved tolerance to alcohols. The invention relates to a genetically modified microbial cell for producing glutamine endogenously by overexpression of one or more enzymes with glutamine synthetase activity. The authors have observed that the presence of glu...

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Bibliographische Detailangaben
Hauptverfasser: DUQUE MARTIN DE OLIVA, María Estrella, ROCA HERNANDEZ, Amalia, UDAONDO DOMINGUEZ, Zulema, RAMOS MARTIN, Juan Luis, CUENCA MARTIN, María del Sol, GOMEZ GARCIA, María Rosario
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Genetically modified microbial cell with improved tolerance to alcohols. The invention relates to a genetically modified microbial cell for producing glutamine endogenously by overexpression of one or more enzymes with glutamine synthetase activity. The authors have observed that the presence of glutamine in the medium improves the tolerance of bacterial cells to alcohols. (Machine-translation by Google Translate, not legally binding) Célula microbiana modificada genéticamente con tolerancia mejorada frente a alcoholes. La invención se refiere a una célula microbiana genéticamente modificada para producir glutamina de manera endógena mediante la sobreexpresión de una o más enzimas con actividad glutamina sintetasa. Los autores han observado que la presencia de glutamina en el medio mejora la tolerancia de las células bacterianas a los alcoholes.