Un derivado de 1-fenil-2,5-dibenzimidazol-5-il-pirrolidina antiviral

{(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-Difluoro-4-[4-(4-fluorofenil)piperidin-1-il]fenil}-5-(6-fluoro-2-{(2S)-1-[N- (metoxicarbonil)-O-metil-1-treonil]pirrolidin-2-il}-1H-benzimidazol-5-il)pirrolidin-2-il]-6-fluoro-1H-benzimidazol-2- il}pirrolidin-1-il]-3-metoxi-1-oxobutan-2-il}carbamato de metilo, o...

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Bibliographische Detailangaben
Hauptverfasser:	Sarris, Kathy, Hutchins, Charles W, Li, Wenke, Carroll, William A, Patel, Sachel V, Randolph, John T, Jinkerson, Tammie K, Krueger, Allan C, Matulenko, Mark A, Degoey, David A, Betebenner, David A, Liu, Dachun, Tufano, Michael D, Kati, Warren M, Keddy, Ryan G, Flentge, Charles A, Maring, Clarence J, Pratt, John K, Bellizzi, Mary E, Hutchinson, Douglas K, Wagner, Rolf, Caspi, Daniel D, Rockway, Todd W, Donner, Pamela L, Motter, Christopher E, Califano, Jean C, Wagaw, Sebel H, Gao, Yi, Woller, Kevin R, Nelson, Lissa T
Format:	Patent
Sprache:	spa
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	{(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-Difluoro-4-[4-(4-fluorofenil)piperidin-1-il]fenil}-5-(6-fluoro-2-{(2S)-1-[N- (metoxicarbonil)-O-metil-1-treonil]pirrolidin-2-il}-1H-benzimidazol-5-il)pirrolidin-2-il]-6-fluoro-1H-benzimidazol-2- il}pirrolidin-1-il]-3-metoxi-1-oxobutan-2-il}carbamato de metilo, o una sal farmacéuticamente aceptable del mismo. To provide: compounds effective in inhibiting replication of Hepatitis C virus ("HCV"); pharmaceutical compositions comprising such compounds, processes of making the compounds, and methods of using such compounds to treat HCV infection.SOLUTION: The invention provides compounds having the formula I in the figure, or pharmaceutically acceptable salts of the compounds.SELECTED DRAWING: None