Productos intermedios para la síntesis de compuestos de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-espiro[4,5]decán-2-ona

Productos intermedios para la síntesis de compuestos de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-espiro[4,5]decán-2-ona

Compuesto de las fórmulas siguientes:**Fórmula** This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparat...

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Hauptverfasser: WU, GEORGE G, WERNE, GERALD, FU, XIAOYONG, CUI, JIAN, CASTELLANOS, LOUIS PETER, SPRAGUE, VICTORIA M, ZENG, LIANSHENG, CHEN, FRANK XING, ORR, ROBERT K, ZHANG, FUCHENG, XIE, JI, POIRIER, MARC, MERGELSBERG, INGRID, CHEN, YUYIN
Format: Patent
Sprache:spa
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Compuesto de las fórmulas siguientes:**Fórmula** This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations.