Artificial dermis, artificial skin, methods for its preparation and its uses (Machine-translation by Google Translate, not legally binding)

Artificial dermis, artificial skin, methods for its preparation and its uses. The present invention relates to an artificial dermis comprising a first layer of coagulated blood plasma gel comprising platelets and dermal cells, and a second gel layer of coagulated blood plasma comprising platelets an...

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Hauptverfasser: GARCIA PEREZ, EVA, JORCANO NOVAL, JOSÉ LUIS, HOLGUIN FERNANDEZ, ALMUDENA, MEANA INFIESTA, ALVARO, MERINO ALVAREZ, SANTOS, GOMEZ LLAMES, SARA, RETOLAZA MUNOA, ARITZ, AZCARATE LETURIA, SABINO, DUARTE GONZALEZ, BLANCA
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Artificial dermis, artificial skin, methods for its preparation and its uses. The present invention relates to an artificial dermis comprising a first layer of coagulated blood plasma gel comprising platelets and dermal cells, and a second gel layer of coagulated blood plasma comprising platelets and dermal cells, and a network of located polymer between the first and second gel layers. The invention also relates to an artificial skin comprising said artificial dermis with at least one layer of epithelial cells. The invention discloses methods for the preparation of the artificial dermis and artificial skin, as well as its uses in the preparation of a medicament, in particular for the treatment of reepithelialization of a patient in need thereof. (Machine-translation by Google Translate, not legally binding) Dermis artificial, piel artificial, métodos para su preparación y sus usos. La presente invención se refiere a una dermis artificial que comprende una primera capa de gel de plasma sanguíneo coagulado que comprende plaquetas y células dérmicas, y una segunda capa de gel de plasma sanguíneo coagulado que comprende plaquetas y células dérmicas, y una red de polímero situada entre la primera y la segunda capas de gel. La invención también se refiere a una piel artificial que comprende dicha dermis artificial con al menos una capa de células epiteliales. La invención desvela métodos para la preparación de la dermis artificial y de la piel artificial, así como sus usos en la preparación de un medicamento, en particular para el tratamiento de reepitelialización de un paciente que lo necesite.