Inmunoterapéuticos polivalentes de alta especificidad basados en anticuerpos modificados y formulación liofilizada inyectable altamente segura y eficaz

The invention is related to the production and development of a lyophilized injectable formulation of modified antibodies or their variants, highly specific neutralizers of heterologous mixtures of proteins, peptides and other organic or inorganic components have different specific activities and ma...

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Bibliographische Detailangaben
Hauptverfasser: SORIA OSORIO, Raúl, LOPEZ DE SILANES PEREZ, Juan
Format: Patent
Sprache:spa
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Beschreibung
Zusammenfassung:The invention is related to the production and development of a lyophilized injectable formulation of modified antibodies or their variants, highly specific neutralizers of heterologous mixtures of proteins, peptides and other organic or inorganic components have different specific activities and may include but are not limited to the venoms of venomous animals. For convenience, we refer to venoms, but all type of venoms was included of land and marine animals. It is also addressed to the production method which includes the hyperimmunization of mammals for the production of highly specific antibodies, the modification (fragmentation) and purification process, and finally the injectable formulation conferring thereon properties of high purity and high specificity.