Péptido derivado de nogina y uso del mismo

Un péptido que presenta una actividad del factor de crecimiento representado por la fórmula general (1): Glu-Leu-Ile-Glu-His-engarce-Arg-Pro-Ala-Asp (1) en la que el engarce comprende residuos aminoacídicos de glicina o de glicina y serina y es de 2-18 aminoácidos de longitud. Disclosed are a noggin...

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Bibliographische Detailangaben
Hauptverfasser: CHUNG, YOUNG JI, HONG, IL, HAN, SANG MIN, KIM, EUN MI, SONG, SANG SU, KIM, YOUNG DEUG, CHO, KYOUNG MI, KIM, SU MI
Format: Patent
Sprache:spa
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Zusammenfassung:Un péptido que presenta una actividad del factor de crecimiento representado por la fórmula general (1): Glu-Leu-Ile-Glu-His-engarce-Arg-Pro-Ala-Asp (1) en la que el engarce comprende residuos aminoacídicos de glicina o de glicina y serina y es de 2-18 aminoácidos de longitud. Disclosed are a noggin-derived peptide and a composition containing the same for promoting hair growth, improving skin conditions, providing anti-inflammatory function, or preventing or treating bone diseases. The disclosed noggin-derived peptide performs a function identical or similar to that of natural human noggin and is superior in stability and skin permeability as compared thereto. The composition containing the peptide of the present disclosure as an active ingredient exhibits remarkably superior effects in treating, preventing or improving growth factor-related symptoms, e.g. hair loss, skin conditions or cut, or treating, preventing or improving growth factor overexpression-related symptoms. Therefore, the superior activity and stability of the peptide of the present disclosure are greatly advantageous in application to medicine, quasi-drugs and cosmetics.