Método de obtención de megacariocitos y plaquetas

The present invention is based on the surprising discovery that the overexpression of the SCL gene, having nucleotide sequence SEQ ID NO: 1, increases the production of megakaryocytes and platelets from stem cells. It has therefore been proven that this increase also occurs using PSCs which, unlike...

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Hauptverfasser:	Ramos Mejía, Verónica, Bueno Uroz, Clara, Romero Escobar, Tamara, Navarro Montero, Oscar, Cobo Pulido, Marién, Ayllón Cases, Verónica, Menéndez Bujan, Pablo, García Toscano, Miguel, Martín Molina, Francisco, Real Luna, Pedro José
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is based on the surprising discovery that the overexpression of the SCL gene, having nucleotide sequence SEQ ID NO: 1, increases the production of megakaryocytes and platelets from stem cells. It has therefore been proven that this increase also occurs using PSCs which, unlike CD34+ HSC cells which have limited expansion capacity, are characterized by an unlimited growth capacity, and can result in the unlimited production of platelets for clinical use.