Composición farmacéutica tópica de mupirocina

Una composición farmacéutica o veterinaria en forma de gel tópico anhidro de mupirocina o de una sal de la misma aceptable para uso farmacéutico o veterinario que comprende: a) una base lipófila seleccionada del grupo que consiste en petrolato, triglicéridos de cadena media, miristato de isopropilo y sus mezclas; b) un bioadhesivo seleccionado del grupo que consiste en polivinilpirrolidona y polimetacrilatos; y c) un disolvente seleccionado del grupo que consiste en etanol, propanol e isopropanol. Anhydrous topical gel composition of mupirocin or its salts comprising: a) a lipophilic base selected from the group consisting of petrolatum, medium-chain triglycerides, isopropyl myristate and mixtures thereof; b) a bioadhesive selected from the group comprising polyvinylpyrrolidone and polymethacrylates; and c) a solvent selected from the group comprising ethanol, propanol, and isopropanol; which is stable and shows an increased residence time of the active ingredient in the skin, resulting in an improved clinical effect in the treatment of bacterial skin infections while maintaining the safety profile of the commercial pharmaceutical product.