Moléculas de unión para las proteínas similares al factor VIII y factor VIII humano

polipéptido que se une a un Factor VIII o un fragmento de este que retiene actividad procoagulante del factor VIII, en donde dicho polipéptido comprende una secuencia de aminoácido seleccionada del grupo que consiste de: Phe-Gly-Cys-Ser-Trp-Leu-Phe-Pro-Cys-Pro-Phe (sec. con núm. de ident.:5); Pro-Hi...

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Hauptverfasser: YU, JINAN, DEETZ, JEFFREY S, KELLEY, BRIAN D, BOOTH, JAMES E, POTTER, DANIEL M
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DEETZ, JEFFREY S
KELLEY, BRIAN D
BOOTH, JAMES E
POTTER, DANIEL M
description polipéptido que se une a un Factor VIII o un fragmento de este que retiene actividad procoagulante del factor VIII, en donde dicho polipéptido comprende una secuencia de aminoácido seleccionada del grupo que consiste de: Phe-Gly-Cys-Ser-Trp-Leu-Phe-Pro-Cys-Pro-Phe (sec. con núm. de ident.:5); Pro-His-Cys-Asn-Trp-Leu-Phe-Pro-Cys-Ser-Leu (sec. con núm. de ident.:6); Arg-Leu-Cys-Ser-Trp-Ile-Ser-Pro-Cys-Ser-Ala (sec. con núm. de ident.:7); Phe-His-Cys-Ile-Gly-Val-Trp-Phe-Cys-Leu-His (sec. con núm. de ident.:8); y Arg-Leu-Cys-Ser-Trp-Val-Ser-Pro-Cys-Ser-Ala (sec. con núm. de ident.:9). Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. Preferred polypeptide binding moieties are particularly disclosed.
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Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. 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Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. 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Pro-His-Cys-Asn-Trp-Leu-Phe-Pro-Cys-Ser-Leu (sec. con núm. de ident.:6); Arg-Leu-Cys-Ser-Trp-Ile-Ser-Pro-Cys-Ser-Ala (sec. con núm. de ident.:7); Phe-His-Cys-Ile-Gly-Val-Trp-Phe-Cys-Leu-His (sec. con núm. de ident.:8); y Arg-Leu-Cys-Ser-Trp-Val-Ser-Pro-Cys-Ser-Ala (sec. con núm. de ident.:9). Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. Preferred polypeptide binding moieties are particularly disclosed.</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
BLASTING
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HEATING
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
LIGHTING
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MECHANICAL ENGINEERING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
PUMPS
PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
SPIRITS
TESTING
THEIR RELEVANT APPARATUS
TRANSPORTING
VINEGAR
WEAPONS
WINE
title Moléculas de unión para las proteínas similares al factor VIII y factor VIII humano
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