Anticuerpo monoclonal anti-CD40

Anticuerpo o fragmento funcional del anticuerpo que se produce mediante el hibridoma KM341-1-19 (n.º de registro FERM BP-7759). The invention is directed to human antibodies that bind CD40 (e.g., human CD40), methods of producing the antibodies and methods of use. Invention human CD40 antibodies inc...

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Hauptverfasser: YOSHIDA, HITOSHI, FORCE, WALKER R, CHEN, XINGJIE, MIKAYAMA, TOSHIFUMI, TAKASHI, NOBUAKI, SCHOENBERGER, STEPHEN P
Format: Patent
Sprache:spa
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Zusammenfassung:Anticuerpo o fragmento funcional del anticuerpo que se produce mediante el hibridoma KM341-1-19 (n.º de registro FERM BP-7759). The invention is directed to human antibodies that bind CD40 (e.g., human CD40), methods of producing the antibodies and methods of use. Invention human CD40 antibodies include antibodies that can modulate one or more activities of CD40, such as increasing or decreasing cell proliferation. Invention human CD40 antibodies are therefore useful for increasing or decreasing a CD40 activity in order to alter CD40 activity in vivo.