Conjugados de anticuerpo-fármaco y su uso

Conjugados de anticuerpo-fármaco y su uso

Un compuesto seleccionado de entre: **Fórmula** The present disclosure provides antibody-drug conjugates that are potent cytotoxins, wherein the drug is linked to the antibody through a linker. The disclosure is also directed to compositions containing the antibody-drug conjugates, and to methods of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PAN, CHIN, CHEN, LIANG, CARDARELLI, JOSEPHINE, GUERLAVAIS, VINCENT, HORGAN, KILIAN, HUANG, HAICHUN, BOYD, SHARON, SUFI, BILAL, KING, DAVID, GANWAR, SANJEEV
Format: Patent
Sprache:spa
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Un compuesto seleccionado de entre: **Fórmula** The present disclosure provides antibody-drug conjugates that are potent cytotoxins, wherein the drug is linked to the antibody through a linker. The disclosure is also directed to compositions containing the antibody-drug conjugates, and to methods of treatment using them.