Síntesis de éteres fluorados

Un procedimiento para la preparación de 2-difluorometoxi-1,1,1,2-tetrafluoroetano (desflurano) de fórmula: CF3-CHF-O-CF2H que comprende hacer reaccionar 2-cloro-2-difluorometoxi-1,1,1-trifluoroetano (isoflurano) de fórmula:CF3-CHCl-O-CF2H con HF anhidro en presencia de un catalizador de cromia que comprende cromo que tiene una valencia de 3 a 6 yestá seleccionado entre óxidos de cromo, haluros de cromo, óxidos de cromo tratados con haluros y mezclas delos mismos. A process for preparing fluorinated ethers, such as desflurane, comprises reacting the corresponding chlorinated ether, such as isoflurane, with anhydrous hydrogen fluoride in the vapor phase in the presence of chromia catalyst. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims.