PROCEDIMIENTO PARA LA SINTESIS DE LACTONAS DERIVADAS DEL ACIDO p-HIDROXIFENIL PROPIONICO MEJORADO

The present invention relates to improvements to the main patent p201001288 by "process for the synthesis of lactones derived from p-hydroxyphenyl propionic acid", wherein the improved process includes the following steps: A) oxidation of the compound of formula (IV), or the corresponding...

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Bibliographische Detailangaben
Hauptverfasser: PIVEL RANIERI, JUAN PABLO, NOVELLA ROBISCO, JOSE LUIS, FERRER CUESTA, JUAN MANUEL, ALVAREZ-BUILLA GOMEZ, JULIO, MATIA MARTIN, MA PAZ
Format: Patent
Sprache:spa
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Zusammenfassung:The present invention relates to improvements to the main patent p201001288 by "process for the synthesis of lactones derived from p-hydroxyphenyl propionic acid", wherein the improved process includes the following steps: A) oxidation of the compound of formula (IV), or the corresponding one of the naphthyl series, where n can take values 1, 2 and 3 and r can be h or ch3 in the presence of so 3 - pyridine, at 0ºC and in a solvent mixture dmso/dichloromethane, B) treatment of the product obtained in the previous step with the brominated derivative (II) in the presence of a metal and a solvent or mixture of solvents. (Machine-translation by Google Translate, not legally binding)