New hydroxyphenylacetaldehyde dehydrogenase, nucleic acid that codifies and vectors and recombinant microorganisms that express it (Machine-translation by Google Translate, not legally binding)

New hydroxyphenylacetaldehyde dehydrogenase, nucleic acid encoding it and vectors and recombinant microorganisms that express it. The new hydroxyphenylacetaldehyde dehydrogenase is part of a bacterial degradation pathway of tyramine and/or dopamine to pyruvic acid and succinic acid hitherto unknown....

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Hauptverfasser:	LUENGO RODRIGUEZ, JOSE MARIA, RODRIGUEZ OLIVERA, ELIAS, ARCOS RODRIGUEZ, MARIO, NAHARRO CARRASCO, GERMAN
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL RIPENING OF FRUIT OR VEGETABLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES MAKING THEREOF METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MILK OR CHEESE SUBSTITUTES MUTATION OR GENETIC ENGINEERING PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT,VEGETABLES, EDIBLE SEEDS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THE PRESERVED, RIPENED, OR CANNED PRODUCTS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	New hydroxyphenylacetaldehyde dehydrogenase, nucleic acid encoding it and vectors and recombinant microorganisms that express it. The new hydroxyphenylacetaldehyde dehydrogenase is part of a bacterial degradation pathway of tyramine and/or dopamine to pyruvic acid and succinic acid hitherto unknown. It acts after the tyramine oxidase that transforms tyramine or dopamine into 4-hydroxyphenylacetaldehyde and 3,4-dihydroxyphenylacetaldehyde, generating from them 4-hydroxyphenylacetic acid and 3,4-hydroxyphenylacetic acid, respectively. Thus, it can be used in methods directed to decrease the amount of tyramine and/or dopamine, for example in foods. The invention also relates to the nucleic acid molecules encoding the enzyme, the vectors that allow its expression and to recombinant microorganisms transformed with said vectors. (Machine-translation by Google Translate, not legally binding) Nueva hidroxifenilacetaldehído deshidrogenasa, ácido nucleico que la codifica y vectores y microorganismos recombinantes que la expresan. La nueva hidroxifenilacetaldehído deshidrogenasa forma parte de una vía bacteriana de degradación de tiramina y/o dopamina hasta ácido pirúvico y ácido succínico desconocida hasta ahora. Actúa tras la tiramina oxidasa que transforma tiramina o dopamina en 4-hidroxifenilacetaldehído y 3,4-dihidroxifenilacetaldehído, generando a partir de ellos ácido 4-hidroxifenilacético y 3,4-hidroxifenilacético, respectivamente. Así, puede usarse en procedimientos dirigidos a disminuir la cantidad de tiramina y/o dopamina, por ejemplo en alimentos. La invención se refiere también a las moléculas de ácido nucleico que codifican la enzima, los vectores que permitan su expresión y a microorganismos recombinantes transformados con dichos vectores.