METODO PARA EL PRONOSTICO DE TUMORES DEL DESARROLLO Y USO DE INHIBIDORES DE LA METILACION GENICA PARA EL TRATAMIENTO DE LOS MISMOS

Method for the prognosis of tumors of the development and use of inhibitors of gene methylation for the treatment thereof. The present invention pertains to the field of prognosis and therapy of pediatric or developmental tumors. Specifically, it refers to a method to establish the prognosis of deve...

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Bibliographische Detailangaben
Hauptverfasser:	ORDONEZ GARCIA, JOSE LUIS, DE TORRES GOMEZ-PALLETE, CARMEN, SAYAGUES MANZANO, JOSE MARIA, DE ALAVA CASADO, ENRIQUE, OTERO MOTA, ANA PASTORA, SEVILLANO GONZALEZ, MARIA VICTORIA
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Method for the prognosis of tumors of the development and use of inhibitors of gene methylation for the treatment thereof. The present invention pertains to the field of prognosis and therapy of pediatric or developmental tumors. Specifically, it refers to a method to establish the prognosis of developmental tumors based on the analysis of the mechanisms of inactivation of the calcium sensor receptor (car) gene that include the determination of the methylation status of its promoter 2 and the analysis of the allelic state of the locus of the car gene, as well as the use of dna methyltransferase inhibitors and deacetylation of histones for the treatment of pediatric tumors. (Machine-translation by Google Translate, not legally binding)