MODELO HUMANIZADO DE PSORIASIS

The invention relates to a novel humanised animal psoriasis model. Said model is generated by means of the grafting of humanised skin equivalents in the animal, the injection of T lymphocytes and cytokines involved in the generation of the disease in humans, and the implementation of the tape-stripp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	CARRETERO TRILLO, MARTA, MEANA INFIESTA, ALVARO, GARCIA DIEZ, MARTA, JORCANO NOVAL, JOSE LUIS, LARCHER LAGUZZI, FERNANDO, GUERRERO ASPIZUA, SARA, DEL RIO NECHAEVSKY, MARCELA
Format:	Patent
Sprache:	spa
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING FORESTRY HUMAN NECESSITIES HUNTING INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING NEW BREEDS OF ANIMALS PHYSICS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR TESTING TRAPPING
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Beschreibung
Zusammenfassung:	The invention relates to a novel humanised animal psoriasis model. Said model is generated by means of the grafting of humanised skin equivalents in the animal, the injection of T lymphocytes and cytokines involved in the generation of the disease in humans, and the implementation of the tape-stripping technique for damaging said grafted equivalents. Said model can be used to study the disease and to identify and evaluate the efficiency of the compounds in controlling said disease.