Method of obtaining useful data for the prediction of clinical response to a treatment of a patient with cancer. (Machine-translation by Google Translate, not legally binding)

Method for the prediction of clinical response to a treatment of a patient with cancer. The present invention is within the field of molecular biology and medicine. Specifically, it relates to a method for predicting response to a treatment comprising a platinum derivative and a taxane of a cancer p...

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Bibliographische Detailangaben
Hauptverfasser:	REDONDO SANCHEZ, ANDRES, BARRIUSO FEIJOO, JORGE, MENDIOLA SABIO, MARTA, HARDISSON HERNAEZ, DAVID, FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO LA PAZ
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Method for the prediction of clinical response to a treatment of a patient with cancer. The present invention is within the field of molecular biology and medicine. Specifically, it relates to a method for predicting response to a treatment comprising a platinum derivative and a taxane of a cancer patient, by analyzing the expression profile of the genes cav1, cxcl1, edn3, egf, epor, fgf2, nrp1 and timp2. Preferably, this method allows to predict the response to a treatment comprising carboplatin and paclitaxel from a patient with ovarian cancer. (Machine-translation by Google Translate, not legally binding) Método para la predicción de respuesta clínica a un tratamiento de un paciente con cáncer. La presente invención se encuentra dentro del campo de la biología molecular y la medicina. Específicamente se refiere a un método para la predicción de respuesta a un tratamiento que comprende un derivado del platino y un taxano de un paciente con cáncer, mediante el análisis del perfil de expresión de los genes CAV1, CXCL1, EDN3, EGF, EPOR, FGF2, NRP1 y TIMP2. Preferiblemente, este método permite predecir la respuesta a un tratamiento que comprende carboplatino y paclitaxel de una paciente con cáncer de ovario.