PIRAZOLILO TRIDENTADO BIFUNCIONAL QUE CONTIENE LIGANDOS PARA COMPLEJOS DE TRICARBONILO RE, TC Y MN

Agente quelante de la fórmula general: **(Ver fórmula)** en la que m es 0 ó 1 X es NR4; Y es NHR5, SR5 o P(R5)2; R1 y R3 son iguales o diferentes y se seleccionan entre H, alquilo o arilo; R2 es H, COOH, NHR6 o (CH2)nCOOR6; R4 es (CH2)nCOOR6, o (CH2)nOR6; R5 es H, alquilo, arilo, (CH2) nCOOR6, o (CH2)nOR6; R6 es H, alquilo, arilo o una biomolécula; y n es 1,2, 3, 4, 5, 6, 7, 8, 9 ó 10. The present invention relates to a chelating agent of the general formula: (I), wherein m is 0 or 1; X is NR4 or S; Y is SR5, NHR5 or P(R5)2; R1 and R3 are the same or different and are selected from H, alkyl or aryl; R2 is H, COOH, NHR6 or (CH2)nCOOR6; R4 is H, alkyl, aryl, (CH2)nCOOR6 or (CH2)nOR6; R5 is H, alkyl, aryl, (CH2)nCOOR6 or (CH2)nOR6, R6 is H, alkyl or aryl; n is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10; and when R1=R3=CH3, R2, R4 and R5 are not all three H. The invention further relates to a method and kit for the preparation of radiolabeled biomolecules while using the chelating agent.