CONJUGADOS CON ADTIVIDAD ANTIINFLAMATORIA

Un compuesto que tiene la estructura **(Ver fórmula)** o una de sus sales o solvatos farmacéuticamente aceptables. The present invention relates to new compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MARKOVIC, STRIBOR, TOMASKOVIC, LINDA, SIJAN, GORDANA, MERCEP, MLADEN, POLJAK, VISNJA, MESIC, MILAN
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS
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Beschreibung
Zusammenfassung:	Un compuesto que tiene la estructura (Ver fórmula) o una de sus sales o solvatos farmacéuticamente aceptables. The present invention relates to new compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX or XIII: -X 1 -(CH 2 ) m -Q-(CH 2 ) n -X 2 -IX -X 1 -(CH 2 ) m -V-(CH 2 ) p -Q-(CH 2 ) n -X 1 -XIII Z represents the steroid or nonsteroidal subunit derived from steroid or nonsteroidal (NSAID) drugs with anti-inflammatory activity; The present invention relates also to pharmaceutically acceptable salts and solvates of such prepared compounds, to processe and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals.