ANTIBODY PRODUCING MICROORGANISM, ELEMENTS REQUIRED TO OBTAIN SAME, RESULTING ANTIBODIES, THERAPEUTIC COMPOSITIONS AND USE OF THEREOF

The invention relates to a microorganism that produces, secretes and injects single-domain recombinant antibodies into animal or plant eukaryote cells owing to the presence of a gene construction containing a type III secretion signal consisting of a sequence that codes for the first 20 amino acids...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	FERNANDEZ HERRERO LUIS ANGEL, BLANCO TORIBIO ANA
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to a microorganism that produces, secretes and injects single-domain recombinant antibodies into animal or plant eukaryote cells owing to the presence of a gene construction containing a type III secretion signal consisting of a sequence that codes for the first 20 amino acids at the amino-terminal end of protein EspF of Escherichia coli. In addition, said non-pathogenic or attenuated microorganisms can be used to prepare pharmaceutical compositions for the treatment of human or veterinary diseases. Microorganismo productor de anticuerpos, elementos necesarios para su obtención, anticuerpos así producidos, composiciones terapéuticas y sus aplicaciones. La presente invención describe un microorganismo productor, secretor e inyector de anticuerpos recombinantes monodominio en células eucariotas, animales o plantas, gracias a la presencia de una construcción genética que contiene una señal de secreción de tipo III. Además, estos microorganismos no patógenos o atenuados pueden utilizarse en la elaboración de composiciones farmacéuticas para el tratamiento de enfermedades humanas o veterinarias.