Olanzapine preparing method involves methylation of N-desmethylolanzapine with methylating agent in solvent containing dichloromethane and methanol

The method involves methylation of N-desmethylolanzapine with a methylating agent in a solvent. The solvent contains dichloromethane, methanol and their mixtures. The method involves methylation of N-desmethylolanzapine with a methylating agent in a solvent. The solvent contains dichloromethane, methanol and their mixtures. Procedimiento para preparar olanzapina. Un procedimiento para preparar olanzapina, que comprende la metilación de N-desmetilolanzapina con un agente de metilación en un disolvente que comprende diclorometano, metanol o una de sus mezclas.